Kansas City at Carolina 1:00 PM ET
Rested and ready, the Carolina Panthers might find a testy crew of Kansas City Chiefs when Patrick Mahomes plays in Charlotte for the first time Sunday afternoon.
Minnesota at Chicago 1:00 PM ET
Minnesota Vikings coach Kevin O'Connell is well aware of his team's impressive record.
Tennessee at Houston 1:00 PM ET
The Houston Texans hope their midseason malaise is behind them and they get the chance to prove it when they host the lowly Tennessee Titans in an AFC South clash on Sunday.
Detroit at Indianapolis 1:00 PM ET
It's up to Shane Steichen and his Indianapolis Colts staff this week to figure out ways to neutralize the steamrolling Detroit Lions.
New England at Miami 1:00 PM ET
Hitting the road to face the Miami Dolphins has been anything but easy for the New England Patriots over the past 11 years.
Tampa Bay at N.Y. Giants 1:00 PM ET
With a merciless stretch of the schedule concluded and a bye week to freshen up, the Tampa Bay Buccaneers go on the road Sunday and will attempt to end a four-game losing streak against a New York Giants team either in transition or a freefall.
Dallas at Washington 1:00 PM ET
The Washington Commanders are hoping a mini bye can help them get back on track Sunday when they host a fading Dallas Cowboys team coming off a short week.
Denver at Las Vegas 4:05 PM ET
The Las Vegas Raiders will be looking to end a six-game losing streak on Sunday when they host the Denver Broncos.
San Francisco at Green Bay 4:25 PM ET
Brock Purdy and Nick Bosa are not available for the San Francisco 49ers when they enter Green Bay with designs on finding their finishing kick on Sunday afternoon.
Arizona at Seattle 4:25 PM ET
When a team is going bad, a bye week is a welcome respite.
Philadelphia at L.A. Rams 8:20 PM ET
Two of the NFC's hottest teams meet Sunday night as the streaking Philadelphia Eagles visit the Los Angeles Rams.