Jake McCarthy, Lourdes Gurriel Jr., Randal Grichuk and James McCann homered to lead the Arizona Diamondbacks to an 8-2 win against the San Francisco Giants in the second game of their four-game series on Tuesday night in Phoenix.

Geraldo Perdomo added two hits and an RBI for Arizona, which ended a four-game skid with a 4-2 win in the series opener on Monday.

Diamondbacks starter Zac Gallen (6-9) delivered his best start in nearly a month, allowing two runs (one earned) and five hits in seven innings. The 2023 NL All-Star struck out 10 and didn't walk a batter.

Giants right-hander Hayden Birdsong (3-3) permitted four runs (three earned) and three hits in four innings. He struck out six but walked four.

Willy Adames homered for San Francisco, which has lost four in a row to match its season high.

Adames gave the Giants a 1-0 lead when he homered to left-center field with one out in the second, his 10th of the season and the 20th allowed by Gallen.

Daniel Johnson then doubled into the right-center-field gap and continued to third on an errant relay throw before scoring on a weak grounder to first by Patrick Bailey to make it 2-0.

Birdsong allowed his first baserunner when McCann walked with one out in the third. McCann moved to second on a passed ball and scored on a two-out single by Perdomo that sailed just over the head of second baseman Tyler Fitzgerald, cutting the lead to 2-1.

Things continued to unravel for Birdsong in the fourth.

He walked the first two batters on eight pitches before McCarthy smashed a 2-0 fastball into the seats in right-center for a three-run homer and a 4-2 lead.

Carson Seymour took over to start the fifth for San Francisco and got the apparent third out of the inning on a strikeout, but the pitch got away from Bailey for another passed ball, allowing Eugenio Suarez to reach base.

Gurriel then lifted a sinker over the fence in left-center to stretch the lead to 6-2.

Grichuk, who was a late addition to the lineup at designated hitter after Josh Naylor (neck stiffness) was scratched, doubled off the warning track in right-center field in the fourth and blasted a solo home run deep over the fence in center in the sixth to make it 7-2.

McCann followed with a deep home run to left to stretch the margin to 8-2.

--Field Level Media