National Football League
BOXSCORE | PLAY-BY-PLAY | RECAP
San Francisco 16, Arizona 15
When: 4:25 PM ET, Sunday, September 21, 2025
Where: Levi's Stadium, Santa Clara, California
Temperature: 72°
Head Official: John Hussey
Attendance: 70414
Final Scoring Summary
 
Final1234T
Arizona 033915
San Francisco 0601016
SCORING
Scoring Summary
2nd Quarter - 8:45
Arizona FG San Francisco 0 - Arizona 3
Chad Ryland 34 yd. field goal
2nd Quarter - 4:22
San Francisco FG San Francisco 3 - Arizona 3
Eddy Pineiro 38 yd. field goal
2nd Quarter - 0:17
San Francisco FG San Francisco 6 - Arizona 3
Eddy Pineiro 51 yd. field goal
3rd Quarter - 6:37
Arizona FG San Francisco 6 - Arizona 6
Chad Ryland 28 yd. field goal
4th Quarter - 10:50
San Francisco TD San Francisco 13 - Arizona 6
Kyle Juszczyk 1 yd. pass from Mac Jones (Eddy Pineiro kick)
4th Quarter - 8:37
Arizona TD San Francisco 13 - Arizona 13
Trey McBride 1 yd. pass from Kyler Murray (Chad Ryland kick)
4th Quarter - 3:15
Arizona S San Francisco 13 - Arizona 15
Penalty on Dominick Puni enforced in end zone for a safety
4th Quarter - 0:00
San Francisco FG San Francisco 16 - Arizona 15
Eddy Pineiro 35 yd. field goal
TEAMS
Team Stats
  Arizona San Francisco
1st Downs 16 19
Rushing 7 4
Passing 8 14
Penalty 1 1
3rd Down Conversions 5-15 2-10
4th Down Conversions 2-2 1-2
Punts-Average 5-51.6 3-42.7
Return Yards 141 106
Punts-Returns 1-8 3-26
Kickoffs-Returns 4-115 3-80
Int - Returns 1-18 0-0
Penalties-Yards 5-30 5-69
Fumbles-Lost 1-0 0-0
Time of Possession 34:39 25:21
Total Net Yards 260 355
Total Plays 64 62
Average Gain 4.1 5.7
Net Yards Rushing 106 73
Rushes 28 20
Average/Rush 3.8 3.6
Net Yards Passing 154 282
Comp-Att 22-35 27-41
Yards/Pass 4.3 6.7
Sacked-Yards Lost 1-5 1-2
Had Intercepted 0 1
Touchdowns 1 1
Rushing 0 0
Passing 1 1
Other 0 0
Extra Points 1-1 1-1
Field Goals 2-3 3-3
Red Zone Efficiency 1-3-33% 1-4-25%
Goal To Go Efficiency 1-1-100% 1-2-50%
Safeties 1 0
PLAYER STATS
Arizona Cardinals (2-1)
Passing
  COMP/ATT YDS TD INT
K. Murray 22/35 159 1 0
San Francisco 49ers (3-0)
Passing
  COMP/ATT YDS TD INT
M. Jones 27/41 284 1 1
Rushing
  ATT YDS AVG TD LG
T. Benson 10 42 4.2 0 29
K. Murray 6 37 6.2 0 9
J. Conner 9 22 2.4 0 9
G. Dortch 1 5 5.0 0 5
E. Demercado 2 0 0.0 0 1
Rushing
  ATT YDS AVG TD LG
C. McCaffrey 17 52 3.1 0 15
B. Robinson Jr. 2 22 11.0 0 19
M. Jones 1 -1 -1.0 0 -1
Receiving
  TAR REC YDS AVG TD LG
M. Harrison Jr. 6 3 44 14.7 0 32
T. McBride 8 5 43 8.6 1 17
Z. Jones 3 2 25 12.5 0 18
J. Conner 4 3 15 5.0 0 10
T. Benson 4 3 9 3.0 0 5
T. Reiman 3 2 8 4.0 0 6
E. Higgins 1 1 7 7.0 0 7
M. Wilson 2 1 5 5.0 0 5
G. Dortch 2 2 3 1.5 0 2
E. Demercado 1 0 0 0 0 0
Receiving
  TAR REC YDS AVG TD LG
R. Pearsall 11 8 117 14.6 0 34
C. McCaffrey 15 10 88 8.8 0 20
K. Bourne 6 4 38 9.5 0 11
J. Tonges 3 2 21 10.5 0 11
S. Moore 1 1 10 10.0 0 10
M. Valdes-Scantling 1 1 9 9.0 0 9
K. Juszczyk 1 1 1 1.0 1 1
Interceptions
  NO. YDS TD
D. Taylor-Demerson 1 18 0
Interceptions
  NO. YDS TD
No interceptions
Sacks
  NO. YDS
J. Sweat 1.0 2.0
Sacks
  NO. YDS
B. Huff 1.0 5.0
Tackles
  Tk Ast
M. Wilson 6 6
A. Davis-Gaither 5 2
D. Taylor-Demerson 4 0
J. Thompson 4 2
D. Tomlinson 3 0
K. Clark 3 0
B. Baker 3 3
D. Burke 2 0
M. Melton 2 1
P. Mustipher 1 0
J. Burch 1 0
C. Campbell 1 0
D. Robinson 1 0
J. Sweat 1 1
Z. Collins 0 1
B. Browning 0 1
A. Goodlow 0 1
D. Stills 0 1
Tackles
  Tk Ast
F. Warner 5 6
D. Winters 4 4
J. Pinnock 3 0
D. Lenoir 3 0
U. Stout 3 2
M. Williams 2 0
B. Huff 2 3
S. Okuayinonu 2 5
M. Sigle 2 5
C. West 1 1
J. Elliott 1 2
J. Brown 1 2
R. Green 1 3
D. Luter Jr. 0 1
L. Gifford 0 1
K. Davis 0 2
N. Bosa 0 2
Tackles For Loss
  NO.
D. Tomlinson 1.0
M. Wilson 1.0
J. Sweat 1.0
Tackles For Loss
  NO.
J. Elliott 1.0
D. Lenoir 1.0
M. Williams 1.0
B. Huff 1.0
Fumbles
  NO.
J. Conner 1
Fumbles
  NO.
No fumbles