National Football League
MATCHUP
Arizona (2-3-0) at Indianapolis (4-1-0)
Stats: Overall | Home/Away | Last 3 | Grass/Turf | Last 3 Home/Away
Records: ATS | Over/Under
Teams: Arizona Cardinals | Indianapolis Colts
Summary
1:00 PM ET W‑L ATS H A AF AA O/U
Arizona 2-3 3-2-0 1-2 1-1 20.6 19.2 2-3-0
Indianapolis 4-1 4-1-0 3-0 1-1 32.6 17.8 2-3-0
Live Odds | All Odds
Home O/U
Opening line 1.5 -110 47.5 -108
FanDuel OFF OFF
Westgate OFF OFF
Wynn OFF OFF
Best home line Recent line moves
Recent Trends
Arizona:
  • Under is 35-17-1 in ARI last 53 games on fieldturf.
Indianapolis:
  • Over is 8-2 in IND last 10 games in Week 6.
  • IND are 7-3 ATS vs. a team with a losing record.
  • Over is 7-3 in IND last 10 games overall.
Quickchart Matchup
Arizona Arizona Off vs  Indianapolis Indianapolis Def
Arizona 288.4 yards
Indianapolis 315 yards
Arizona 4.8 yards/rush
Indianapolis 4.5 yards/rush
Arizona 5.3 yards/attempt
Indianapolis 6.2 yards/attempt
Indianapolis Indianapolis Off vs  Arizona Arizona Def
Indianapolis 381.2 yards
Arizona 346.6 yards
Indianapolis 4.4 yards/rush
Arizona 3.9 yards/rush
Indianapolis 8.3 yards/attempt
Arizona 6.1 yards/attempt
Quarterbacks
Arizona Yds Comp % Y/A TD/Int Rate
K. Murray 962 68.32 6.0 6/3 88.6
J. Brissett 0 0.00 0.0 0/0 39.6
Indianapolis Yds Comp % Y/A TD/Int Rate
D. Jones 1290 71.33 8.6 6/2 105.1
A. Richardson 9 50.00 4.5 0/0 62.5
R. Leonard 0 0.00 0.0 0/0 -
ATS Records | In Depth
  W‑L ATS H A Grass Turf
ARI
IND		 2‑3
4‑1		 3‑2‑0
4‑1‑0		 1‑2‑0
3‑0‑0		 2‑0‑0
1‑1‑0		 2‑2‑0
1‑0‑0		 1‑0‑0
3‑1‑0
Overall Stats | In Depth
Off Avg Yards Pass Rush Y/R Y/A
ARI
IND		 20.6
32.6		 288.4
381.2		 170.2
253.0		 118.2
128.2		 4.8
4.4		 5.3
8.3
Def Avg Yards Pass Rush Y/R Y/A
ARI
IND		 19.2
17.8		 346.6
315.0		 254.2
217.0		 92.4
98.0		 3.9
4.5		 6.1
6.2
Home/Away Stats | In Depth | Last 3 H/A
Off Avg Yards Pass Rush Y/R Y/A
ARI
IND		 17.5
34.0		 268.0
402.7		 142.0
263.0		 126.0
139.7		 4.6
4.3		 4.4
8.3
Def Avg Yards Pass Rush Y/R Y/A
ARI
IND		 14.5
14.0		 335.0
277.0		 245.0
176.3		 90.0
100.7		 4.3
5.0		 5.6
5.5
Over/Under Records | In Depth
  O/U H A Grass Turf Tot
ARI
IND		 2-3-0
2-3-0		 2-1-0
1-2-0		 0-2-0
1-1-0		 2-2-0
1-0-0		 0-1-0
1-3-0		 39.8
50.4
Last 3 Stats | In Depth
Off Avg Yards Pass Rush Y/R Y/A
ARI
IND		 18.7
33.7		 291.0
338.3		 170.0
232.3		 121.0
106.0		 4.9
4.3		 4.7
7.7
Def Avg Yards Pass Rush Y/R Y/A
ARI
IND		 20.3
17.7		 355.3
346.7		 253.3
248.7		 102.0
98.0		 3.9
4.0		 7.2
6.5
Grass/Turf Stats | In Depth
Off Avg Yards Pass Rush Y/R Y/A
ARI
IND		 20.0
30.5		 276.0
385.2		 130.0
259.2		 146.0
126.0		 5.4
4.3		 4.5
8.1
Def Avg Yards Pass Rush Y/R Y/A
ARI
IND		 13.0
17.2		 315.0
323.2		 208.0
222.2		 107.0
101.0		 4.9
4.6		 4.5
6.4
Injuries
Arizona
Player   Status/Updated Notes
Max Melton CB Ques Oct 12 - Hamstring - 10/5/25 Melton is dealing with a hamstring injury, and it is undetermined if he will be active against the Colts on Sunday, October 12th.
Jon Gaines II OL Ques Oct 12 - Finger - 10/5/25 Gaines II is nursing a finger injury, and it remains to be seen if he will return to action against the Colts on Sunday, October 12th.
Darius Robinson DT Ques Oct 12 - Pectoral - 10/5/25 Robinson is dealing with a pectoral injury, and it is unknown if he will play against the Colts on Sunday, October 12th.
Kelvin Beachum OL Ques Oct 12 - Knee - 10/5/25 Beachum is dealing with a knee injury, and it is unclear if he will dress against the Colts on Sunday, October 12th.
Evan Brown OL Ques Oct 12 - Hamstring - 10/5/25 Brown is nursing with a hamstring injury, and it has yet to be established if he will be active against the Colts on Sunday, October 12th.
Paris Johnson Jr. OL Ques Oct 12 - Knee - 10/5/25 Johnson Jr. is dealing with a knee injury, and it is undetermined if he will be active against the Colts on Sunday, October 12th.
Elijah Jones CB Ques Oct 12 - Ankle - 10/5/25 Jones is bothered by an ankle injury, and it is undetermined if he will be active against the Colts on Sunday, October 12th.
Tip Reiman TE Out indefinitely - Ankle - 10/8/25 Reiman has been added to the injured reserve list due to an ankle injury, and it is unknown when he will be activated.
Trey Benson RB Early Nov - Knee - 10/4/25 Benson has hit the injured reserve list with a knee injury, and he will be out of action till early November.
James Conner RB Out indefinitely - Foot - 9/23/25 Conner has been placed on injured reserve list with a foot injury, and he will miss an extended period.
L.J. Collier DL Out indefinitely - Knee - 9/17/25 Collier is placed on the injured reserve list with a knee injury, and a timetable for return has yet to be established.
Garrett Williams CB Out indefinitely - Knee - 9/17/25 Williams is placed on the injured reserve list with a knee injury, and he will miss an undetermined length of time.
Justin Jones DL Out indefinitely - Knee - 8/28/25 Jones is placed on the injured reserve list with a knee injury, and he will miss an undetermined length of time.
Hayden Conner OL Out indefinitely - Knee - 8/27/25 Conner Has been entered on the injured reserve list with a knee injury, and team officials have yet to provide an exact return date.
Christian Jones OT Out indefinitely - Knee - 8/27/25 Jones has hit the injured reserve list due to a knee injury, and a timetable for return has yet to be established.
Will Hernandez G Out indefinitely - Knee - 9/26/25 Hernandez has been placed on the PUP list while recovering from a Knee-ACL injury, and team officials have yet to provide an exact return date.
Valentin Senn OL Out indefinitely - Undisclosed - 8/4/25 Senn has hit the injured reserve list with an undisclosed injury, and he is without a definitive timetable for return.
Joey Blount S out for season - Neck - 9/10/25 Blount has hit the injured list due to a neck and also concussion injury, and he has been shut down for the remainder of the season.
Sean Murphy-Bunting CB Out indefinitely - Knee - 9/26/25 Murphy-Bunting has been placed on the NFI list with a knee injury, and it is unclear how long he will be idle.
Starling Thomas V CB Out indefinitely - Knee - 7/27/25 Thomas V has been placed on the injured reserve list with a knee-ACL injury, and he is without a definitive timetable for his return.
J.J. Russell LB out for season - Head - 8/27/25 Russell has been added to the injured reserve list due to a concussion, and is projected to miss the remainder of the season.
Bilal Nichols DT Out indefinitely - Neck - 7/24/25 Nichols has been placed on the PUP list while recovering from a Neck injury, and it is unknown when he will be activated.
Walter Nolen III DT Out indefinitely - Calf - 7/24/25 Nolen has been ticketed for the PUP list while recovering from a calf injury, and it is unknown when he will be activated.
BJ Ojulari LB Out indefinitely - Knee - 7/24/25 Ojulari has been ticketed for the PUP list while recovering from a knee - ACL, and the team officials have yet to provide an exact return date.
Indianapolis
Player   Status/Updated Notes
Tyler Goodson RB Ques Oct 12 - Groin - 10/5/25 Goodson is nursing due to a groin injury, and it is unclear whether he will play against the Cardinals on Sunday, October 12th.
Alec Pierce WR Ques Oct 12 - Concussion - 10/5/25 Pierce is battling a concussion injury, and it remains to be seen if he will be active against the Cardinals on Sunday, October 12th.
Matt Goncalves G Ques Oct 12 - Toe - 10/5/25 Goncalves is managing a toe injury, and it is unclear if he will be active against the Cardinals on Sunday, October 12th.
Kenny Moore II CB Out indefinitely - Calf - 9/22/25 Moore II suffered a calf injury, and he will be out of action for couple of weeks.
Joe Bachie LB Out indefinitely - Undisclosed - 10/8/25 Bachie has been placed on injured reserve with an undisclosed injury, and he will miss an extended period.
Spencer Shrader K out for season - Knee - 10/8/25 Shrader has hit the injured reserve list with a knee injury, and has been shut down for the remainder of the season.
Daniel Scott S Out indefinitely - Knee - 10/4/25 Scott is placed on the injured reserve list with a knee injury, and there is no timetable for return.
Jacob Phillips LB out for season - Bicep - 8/19/25 Phillips has placed on the injured reserve list due to a bicep injury, and he will be out of action for the remainder of the season.
Blake Freeland OT out for season - Leg - 10/3/25 Freeland has been designated for the injured reserve list with a leg injury, and he is expected to miss the remainder of the season.
Hunter Wohler S out for season - Foot - 8/19/25 Wohler has landed on the injured reserve list due to a foot injury, and he has been shut down for the remainder of the season.
D.J. Montgomery WR out for season - Undisclosed - 10/3/25 Montgomery is placed on the injured reserve list with an undisclosed injury, and he is likely to miss the remainder of the season.
Justin Walley CB out for season - Knee - 8/9/25 Walley has placed on the injured reserve list due to a torn ACL, and he will be out of action for the remainder of the season.
Jack Wilson OT Out indefinitely - Undisclosed - 7/29/25 Wilson has been moved to the injured reserve list with an undisclosed injury and is expected to miss the remainder of the season.
Salvon Ahmed RB out for season - Leg - 8/9/25 Ahmed has hit the injured reserve list due to an ankle injury, and has been shut down for the remainder of the season.
Jaylon Jones CB Out indefinitely - Hamstring - 9/13/25 Jones has been placed on injured reserve with a hamstring injury, and he will miss an extended period.
Jaylon Carlies LB Out indefinitely - Ankle - 8/28/25 Carlies has popped up on the injured reserve list due to an ankle injury, and it is unclear how long he will be idle.
Recent Meetings
  Arizona Indianapolis
Date Away/Home Line ATS Tot Rus Pas Tot Rus Pas
8/17/24 ARI (13) - IND (21) 2.5/36 IND/U 232 100 132 356 166 190
12/25/21 IND (22) - ARI (16) -3/48 IND/U 378 133 245 346 126 220
9/17/17 ARI (16) - IND (13) 7/44 IND/U 389 83 306 266 76 190
11/24/13 IND (11) - ARI (40) -3.5/44.5 ARI/O 410 120 290 239 80 159
9/27/09 IND (31) - ARI (10) -3/49 IND/U 323 24 299 505 126 379
1/1/06 ARI (13) - IND (17) -7.5/45 ARI/U 413 129 284 218 11 207
9/1/96 ARI (13) - IND (20) -9/37 ARI/U 310 84 226 312 74 238
12/20/92 ARI (13) - IND (16) -2.5/35 IND/U 0 0 0 0 0 0
12/2/90 IND (17) - ARI (20) -2.5/40 ARI/U 0 0 0 0 0 0
9/16/84 ARI (34) - IND (33) -/- -/- 0 0 0 0 0 0
Arizona  Last 10
  Yards Per Play
Date vs Score Line ATS Tot Rus Pas Tot Rus Pas
10/5/25 TEN L 21-22 2/41.5 W/O 33 90 -57 0.7 2.5 -0.4
9/25/25 SEA L 20-23 1.5/43.5 L/U -131 -66 -65 -1.9 0.8 -4.8
9/21/25 @ SF L 15-16 1.5/44.5 W/U -95 33 -128 -1.7 0.1 -2.5
9/14/25 CAR W 27-22 -7/45.5 L/O -59 33 -92 1.5 1.1 2.9
9/7/25 @ NO W 20-13 -5/42.5 W/U -39 39 -78 0.3 0.5 -0.0
8/23/25 LV W 20-10 3/38 W/U 28 107 -79 1.7 4.2 -1.5
8/16/25 @ DEN L 7-27 3/37 L/U -427 -131 -296 -4.9 -3.1 -6.6
8/9/25 KC W 20-17 2.5/40.5 W/U 106 48 58 1.8 -0.4 4.7
1/5/25 SF W 47-24 -4.5/43.5 W/O -43 13 -56 0.2 0.7 -0.0
12/28/24 @ LAR L 9-13 6.5/48.5 W/U 139 45 94 0.9 2.0 -0.0
Indianapolis  Last 10
  Yards Per Play
Date vs Score Line ATS Tot Rus Pas Tot Rus Pas
10/5/25 LV W 40-6 -7/46.5 W/U 21 -10 31 0.7 -0.4 1.6
9/28/25 @ LAR L 20-27 3.5/49.5 L/U -129 -17 -112 -0.7 0.1 -1.3
9/21/25 @ TEN W 41-20 -6/42.5 W/O 83 51 32 2.3 1.2 4.0
9/14/25 DEN W 29-28 2.5/43.5 W/O 149 49 100 1.2 0.3 2.1
9/7/25 MIA W 33-8 1/47 W/U 207 78 129 1.2 -2.6 4.7
8/23/25 @ CIN W 41-14 2.5/36.5 W/O 244 65 179 2.0 -0.1 3.9
8/16/25 GB L 19-23 -6/39 L/O 4 -66 70 0.7 0.7 -0.3
8/7/25 @ BAL L 16-24 -6/35.5 L/O 140 -51 191 0.9 0.3 1.9
1/5/25 JAC W 26-23 -3.5/46 L/O 110 64 46 1.0 1.9 -0.1
12/29/24 @ NYG L 33-45 -7.5/40.5 L/O 57 46 11 -1.1 1.2 -5.0
Abbreviations Legend